Anti-hyperlipidemia drug improves brain connectivity in mouse models of schizophrenia

New therapies that improve connectivity and circuitry in the brain of people with schizophrenia could result from the discovery by a RIKEN-led team of a potential new target for drugs to treat the psychiatric disorder. Treatment for schizophrenia has not changed much in 60 years. Doctors still generally prescribe medicines designed to tame psychosis by […]

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Greensill Capital eyeing insolvency protection in Australia

Troubled supply chain finance firm Greensill Capital is seeking insolvency protection in Australia, the Financial Times reported on Tuesday, after Credit Suisse suspended $10 billion of funds linked to the London-based company’s lending operations. Greensill, backed by Japan’s SoftBank Group, is looking to invoke a “safe harbour” protection in Australia where its parent company is […]

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New method facilitates development of antibody-based drugs

In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases. Now, researchers at Lund University in Sweden have developed a new, efficient method based on the ‘genetic scissors’ CRISPR-Cas9 that facilitates antibody development. The discovery is published in Nature Communications. Antibody drugs are the fastest growing class of drug, and several […]

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